Date

2017-04-06

Protocol

Protocol changed

Item Changed

Intervention(s) planned

Previous Version

1. Stage I -Diabetic patients will be randomized and grouped to receive Cinnamomum zeylanicum and placebo with different doses 2. Stage II - Volunteers will receive Cinnamomum zeylanicum for 3 months with escalating doses(1g, 3g, 6g daily)

Next Version

Study setting: Department of Pharmacology, Faculty of Medicine, University of Colombo Details of the interventional product: Oral capsules containing cinnamon (85,250, 500mg) once daily for 3 months in monthly escalating doses as given below 85mg 1st month 250mg 2nd month 500mg 3rd month