Date

2025-06-25

Protocol

Protocol changed

Item Changed

Primary outcome(s)

Previous Version

Urinary protein to creatinine ratio (uPCR) in a 24-hour collection [Time Frame: At 9 months]

Next Version

To compare the relative change from baseline in uPCR achieved with sibeprenlimab versus placebo added to SOC, after 9 months of SC administration. [Efficacy: Ratio of uPCR at 9 months compared with baseline, based on 24-hour urine collection]