Date

2026-02-16

Protocol

Protocol changed

Item Changed

Secondary Outcome

Previous Version

1. Change in urine albumin creatinine ratio 2. Change in serum creatinine 3. HbA1C 4. Fasting blood glucose 5. Systolic and diastolic blood pressure 6. Body weight 7. Quality of life measured by EQ-5D-5L. 8. Anxiety and depression symptoms measured by HADS

Next Version

Urine albumin creatinine ratio (mg/g); 2. Serum creatinine (µmol/L); 3. Glycosylated Haemoglobin (HbA1c) (%); 4. Fasting blood glucose (mmol/L); 5. Systolic and diastolic blood pressure (mmHg); 6. Body weight (kg); and 7. Quality of life measured by EQ-5D-5L. 8. Anxiety and depression symptoms measured by HADS.